Nexium Esomeprazole is a drug used to treat patients that have medical conditions due to excessive acid production in the stomach. Esomeprazole is sold by the manufacturer AstraZeneca in the form of 40mg tablets under the name Nexium. It is used in the treatment of heartburn, duodenal ulcers and also Gastro Esophageal Reflux Disease (GERD). Esomeprazole works by blocking acid production in the stomach.

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